This relatively affluent, middle-class neighborhood on Chicago's south side offers spacious homes in a quiet, pocketsize residential setting. Near enough to the highway to allow easy transportation into the heart of the city, without all the hubbub of being right on top of a freeway. Pill Hill was at one time the prime address for area doctors who worked at the nearby South Chicago Hospital (hence the name Pill Hill — as in prescription pills). These days the neighborhood welcomes a variety of residents.

Pill Hill is a part of Calumet Heights.